TLR

How the Viruses Within Us Protect Us From Other Viruses

by Gertrud U. Rey Did you know that eight percent of the human genome consists of DNA sequences that are derived from retroviruses? These “endogenous retroviruses” (ERVs) represent concrete evidence for retroviral infections that occurred in our ancestors. Although ERVs have no viral activity, an accumulating body of evidence suggests that they are not entirely …

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Toll to the Rescue

by Gertrud U. Rey Transmissible spongiform encephalopathies (TSEs) include a variety of fatal neurodegenerative diseases caused by infectious proteins called prions. Although prions are not viruses, their ability to self-propagate without a nucleic acid intermediate has always fascinated virologists, causing them to adopt prions into their repertoire of pathogenic agents. Common TSEs comprise scrapie in …

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