susceptibility

TWiV 441: Don’t ChrY for me influenza

The Beacons of Viral Education (aka the TWiVoners) reveal a cost of being a male mouse – the Y chromosome regulates their susceptibility to influenza virus infection. You can find TWiV #441 at microbe.tv/twiv, or listen below. Click arrow to play Download TWiV 441 (72 MB .mp3, 119 min) Subscribe (free): iTunes, RSS, email Become a patron of TWiV!

Giving your neighbor the gift of virus susceptibility

Virus infections initiate when virions bind to receptors on the cell surface. It is well known that cells can be made susceptible to infection by providing DNA encoding the virus receptor. For example, mice cannot be infected with poliovirus, but become susceptible if they are given the human poliovirus receptor gene. Now we have learned that providing the receptor protein …

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