Virology lecture #3: Genomes and genetics
Download: .wmv (333 MB) | .mp4 (75 MB) Visit the virology W3310 home page for a complete list of course resources.
RNA
TWiV 65: Matt’s bats
Hosts: Vincent Racaniello, Alan Dove, and Matthew Frieman Vincent, Alan, and Matt discuss a project to study the RNA virome of Northeastern American bats, failure to detect XMRV in UK chronic fatigue syndrome patients, and DNA of bornavirus, an RNA virus, in mammalian genomes. This episode is sponsored by Data Robotics Inc. To receive $50 …
What if influenza virus did not reassort?
Would influenza virus be the same pathogen if it could not undergo reassortment of its segmented RNA genome? This is the question being asked in the wake of the development of a method to prevent the free assortment of influenza viral RNAs. The process of influenza virus replication includes the incorporation of eight viral RNAs …
TWiV 49: Viral genomes
Hosts: Vincent Racaniello and Dick Despommier On episode 49 of the podcast ‘This Week in Virology”, Vincent and Dick continue Virology 101 with a discussion of the seven different types of viral genomes, and how to use the pathway to mRNA to understand viral replication. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV049.mp3″] Click the arrow above to play, or right-click …
Pandemic H1N1 influenza virus outcompetes seasonal strains in ferrets
When more than one influenza A virus subtype is circulating in humans, as has been the case since 1977, there are several possible outcomes. The viruses might co-circulate, one virus might out-compete another, or co-infection of cells with two viruses can lead to the production of genetically distinct viruses by the process of reassortment of …
Pandemic H1N1 influenza virus outcompetes seasonal strains in ferrets Read More »
Why don’t DNA based organisms discard error repair?
The recent series of posts on polymerase error rates and viral evolution has elicited many excellent and thought provoking comments from readers of virology blog. Here is one that I had not thought of before, and which I’ll use on an exam in my virology course: Here’s a tough question. In the follow up blog …
Why don’t DNA based organisms discard error repair? Read More »