Genomes of non-defective viruses range in size from 2,400,000 bp of dsDNA (Pandoravirus salinus) to 1,759 bp of ssDNA (porcine circovirus). Are even smaller viral genomes possible? The subviral agents called viroids provide an answer to this question. Viroids, the smallest known pathogens, are naked, circular, single-stranded RNA molecules that do not encode protein yet replicate …
Viroids, infectious agents that encode no proteins Read More »
En esta clase revisaremos como se sintetizan los pre-RNA mensajeros a partir de sus templados de DNA, y como los pre-mRNA se convierten a mRNAs maduros mediante splicing, poliadenilación, y su exportación del núcleo al citoplasma celular.
Viral genomes are unusual because they can be based on RNA or DNA, in contrast to all cellular life forms, which have DNA as their genetic information. An unusual new virus has been discovered that appears to have sequences from both an RNA and a DNA virus. The new virus was identified during a study …
On episode #180 of the science show This Week in Virology, Vincent, Alan, and Rich review association of an interferon-induced protein with severe influenza, and stabilization of HCV RNA by a microRNA. You can find TWiV #180 at www.microbe.tv/twiv.
Most students of elementary biology will have seen the table at left that depicts the genetic code. HG Khorana was one of several scientists who determined, in the 1960s, the amino acids specified by each three-letter combination of bases. As long as I have been at Columbia University I have had a copy of this …
Download: .wmv (324 MB) | .mp4 (76 MB) Visit the virology W3310 home page for a complete list of course resources.
