RNA interference

TWiV 524: Slicing and dicing with Raul

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Raul Andino joins Vincent and Amy to talk about the finding that a cricket paralysis virus protein restricts RNA-based immunity in insects by regulating the activity and stability of the Argonaute protein. <span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”></span>&lt;span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”&gt;&lt;/span&gt;&amp;lt;span data-mce-type=”bookmark” style=”display: …

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TWiV 475: Everything is viral

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In the first episode for 2018, the TWiV team reviews the amazing virology stories of 2017. <span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”></span> Click arrow to play Download TWiV 475 (67 MB .mp3, 110 min) Subscribe (free): iTunes, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv

TWiV 450: Ben tenOever and RNA out

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Ben tenOever joins the TWiVoli to discuss the evolution of RNA interference and his lab’s finding that RNAse III nucleases, needed for the maturation of cellular RNAs, are an ancient antiviral RNA recognition platform in all domains of life.   Click arrow to play Download TWiV 450 (58 MB .mp3, 96 min) Subscribe (free): iTunes, RSS, email Become a patron of TWiV! Show …

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TWiV 449: The sound of non-silencing

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The TWiV Council explores the finding that facial appearance affects science communication, and evidence that RNA interference confers antiviral immunity in mammalian cells. Click arrow to play Download TWiV 449 (62 MB .mp3, 102 min) Subscribe (free): iTunes, RSS, email Become a patron of TWiV! Full show notes at microbe.tv/twiv

TWiV 433: Poops viruses and worms

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The lovely TWiV team explore evolution of our fecal virome, and the antiviral RNA interference response in the nematode C. elegans. You can find TWiV #433 at microbe.tv/twiv, or listen below. Click arrow to play Download TWiV 433 (65 MB .mp3, 107 min) Subscribe (free): iTunes, RSS, email Become a patron of TWiV!

Transgenic pigs resistant to foot-and-mouth disease

1 Comment / Basic virology, Information / By

Foot-and-mouth disease virus (FMDV) infects cloven-hoofed animals such as cattle, pigs, sheep, goats, and many wild species. The disease caused by this virus is a substantial problem for farmers because infected animals cannot be sold. Transgenic pigs have now been produced which express a short interfering RNA (siRNA) and consequently have reduced susceptibility to infection with FMDV. …

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