On episode #241 of the science show This Week in Virology, Vincent, Alan, Rich and Kathy review how human placental trophoblasts confer viral resistance via exosome-mediated delivery of microRNAs, and isolation of the first human influenza virus in 1933. You can find TWiV #241 at www.microbe.tv/twiv.
On episode #30 of the science show This Week in Microbiology, Vincent, Elio, and Michael review how a toxin from Burkholderia pseudomallei inhibits protein synthesis, and the role of the gut microbiome in modulating insulin resistance in mice lacking an innate immune sensor. You can find TWiM #30 at microbeworld.org/twim.
Hosts: Vincent Racaniello, Michael Schmidt, Arturo Casadevall, Stuart Levy, and David Livermore. Vincent, Michael, Arturo, Stuart, and David converse about antimicrobial resistance and why most fungi do not cause disease, at the 51st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC). [powerpress url=”http://traffic.libsyn.com/twimshow/TWiM016.mp3″] Click the arrow above to play, or right-click to download TWiM 16 (65 MB, …
Hosts: Vincent Racaniello, Cliff Mintz, Michael Schmidt, and Elio Schaecter On episode #6 of the podcast This Week in Microbiology, Vincent, Cliff, Michael and Elio review the use of bacteriophages to manage infections, and the presence of antibiotic resistance genes in bacteriophages from urban sewage and river water. [powerpress url=”http://traffic.libsyn.com/twimshow/TWiM006.mp3″] Click the arrow above to play, …
TWiM 6: Antibacterial therapy with bacteriophage: Reality or fiction? Read More »
The influenza virus neuraminidase (NA) protein is required for virus release from the cell, a property exploited by the antiviral drugs oseltamivir (Tamiflu) and zanamavir (Relenza). During clinical testing of oseltamivir in 2001, some individuals shed drug-resistant viruses with an amino acid change from histidine to tyrosine (H274Y) in NA. Such viruses are not inhibited …
Secondary changes allow spread of oseltamivir resistant influenza virus Read More »
Yesterday the New York Times ran an article on the resistance to Tamiflu of current influenza H1N1 strains circulating in the US. I wrote a post about this issue on 22 December 2008, so I’m happy to see the Times following my lead. But there is an issue with the Times article that I’d like …
