protein structure

TWiV 394: Cards in a hand

Vincent and Alan speak with Erica Ollmann Saphire about her career and her work on understanding the functions of proteins of Ebolaviruses, Marburg virus, and other hemorrhagic fever viruses, at ASM Microbe 2016 in Boston, MA. You can find TWiV #394 at microbe.tv/twiv, or listen or watch the video below. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV394.mp3″] Click arrow to …

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How ZMapp antibodies bind to Ebola virus

ZMapp, a mixture of three antibodies against Ebola virus, became a household name after it was used to treat two Americans who were infected while working in Liberia. The structure of these antibodies bound to the Ebola virus glycoprotein suggest how they inhibit infection and ways to improve ZMapp. The three monoclonal antibodies that comprise ZMapp (called c13C6, c2G4, and c4G7) were …

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