Some antiviral drugs, like acyclovir for treatment of herpes simplex virus infections, are chain terminators that block RNA or DNA synthesis. They are modified nucleotides that can be incorporated into a growing RNA strand, but no additional nucleotides can be added. Amazingly, a cell protein has been found that can synthesize antiviral chain terminators.
Hosts: Vincent Racaniello, Rich Condit, and Alan Dove Vincent, Rich, and Alan continue Virology 101 with a discussion of transcription, the process of making mRNA from a DNA template. Please help us by taking our listener survey. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV162.mp3″] Click the arrow above to play, or right-click to download TWiV 162 (56 MB .mp3, 93 minutes). …
Hosts: Vincent Racaniello, Dickson Despommier, and Rich Condit On episode #106 of the podcast This Week in Virology, Vincent, Dickson, and Rich continue Virology 101 with a second installment of their discussion of how viruses with DNA genomes replicate their genetic information. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV106.mp3″] Click the arrow above to play, or right-click to download TWiV #106 (69 …
Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and David Baltimore Vincent, Alan, and Rich celebrate the 100th episode of the podcast This Week in Virology by talking about viruses with Nobel Laureate David Baltimore. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV100.mp3″] Click the arrow above to play, or right-click to download TWiV #100 (68 MB .mp3, 94 minutes) Subscribe to …
When infection with hepatitis C virus goes from acute to chronic, severe liver disease may occur which requires organ transplantation. Nearly 200 million people are chronically infected with HCV, necessitating approaches to preventing and treating infections. No HCV vaccine is available, and current antiviral therapy consists of administration of interferon plus ribavirin, a combination that …
Download: .wmv (324 MB) | .mp4 (76 MB) Visit the virology W3310 home page for a complete list of course resources.
