Virologist Vincent Racaniello breaks down the first case of polio in the US in nearly a decade.
Daniel Griffin provides a clinical report on COVID-19, then Amy joins us to discuss the 2020 Chemistry Nobel Prize for gene editing using CRISPR/Cas9, continuing circulation of poliovirus in Afghanistan, inborn errors of interferon in patients with severe COVID-19, and listener questions. Click arrow to playDownload TWiV 671 (102 MB .mp3, 170 min)Subscribe (free): iTunes, Google Podcasts, RSS, email Become …
At Aarhus University in Denmark, Vincent speaks with Trine Mogensen, SÃ¸ren Paludan, Ole SÃ¸gaard, and Madalina Carter-Timofte about their careers and their work on sensing herpesviral DNA, immunodeficiencies that predispose to severe viral infections, and the path to a cure for HIV/AIDS. Click arrow to play Download TWiV 570 (61 MB .mp3, 101 min) Subscribe (free): iTunes, Google Podcasts, RSS, email …
Cases of poliomyelitis have been reported in the Philippines 19 years after the country was declared free of the disease. The return of poliomyelitis to the country emphasizes the need to maintain high levels of immunization while polioviruses continue to circulate.
After infection with poliovirus, only about 1% of individuals develop paralysis. I have always wondered whether genetic polymorphisms underlie the rarity of this disease outcome. The results of study carried out in Denmark provide the first insights.
On episode #373 of the science show This Week in Virology, Vincent speaks with Julius about his long career in virology, including his crucial work as part of the team at the University of Pittsburgh that developed the Salk inactivated poliovirus vaccine. You can find TWiV #373 at microbe.tv/twiv. Or you can watch the video below.