pandemic

TWiV 159: Flu gets the REDD light

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit Vincent, Alan, and Rich review concern over an influenza H5N1 transmission experiment, and a new host defense protein against RNA viruses. Please help us by taking our listener survey. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV159.mp3″] Click the arrow above to play, or right-click to download TWiV 159 (48 MB .mp3, 80 minutes). Subscribe …

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Derek Smith on antigenic cartography

Derek Smith, Professor of Infectious Disease Informatics, University of Cambridge, U.K., has developed a method for visualizing antigenic evolution by creating two-dimensional maps in a process called antigenic cartography. These maps are made with data that provide information on the antigenic properties of the pathogen. In the case of influenza virus, the data come from …

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TWiV 112: Creating a killer poxvirus

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit On episode #112 of the podcast This Week in Virology, Vincent, Alan, and Rich review the making of a virulent poxvirus by insertion of the gene encoding IL-4, and severe 2009 H1N1 influenza due to pathogenic immune complexes. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV112.mp3″] Click the arrow above to play, or right-click to …

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Pandemic influenza vaccine was too late in 2009

Influenza researcher Peter Palese visited yesterday and spoke about “Pandemic influenza: Past and Future”. A key part of his talk was a review of his efforts to produce a universal influenza vaccine which protects against all strains. He used the following graph to make the point that when influenza pandemic strains emerge, there is insufficient …

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Thoughts on this season’s influenza vaccine

After my lecture on influenza pathogenesis and evolution at the Northeast Laboratory Conference 2010 in Portland, Maine, I was asked if it is necessary to receive the influenza vaccine every year. This question was precipitated by my statement that the 2010-11 trivalent influenza vaccine contains the same swine-origin H1N1 strain as last year€™s monovalent vaccine. …

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