Polio in New York
Virologist Vincent Racaniello breaks down the first case of polio in the US in nearly a decade.
OPV
A genetically stable attenuated poliovirus vaccine
Eradication of poliomyelitis appears to be on track: types 2 and 3 polioviruses have been declared eradicated, and in the past 12 months there have been just 338 cases of type 1 polio in Afghanistan and Pakistan. But there have also been 491 cases of polio caused by the type 2 Sabin vaccine. The development …
A genetically stable attenuated poliovirus vaccine Read More »
Wild poliovirus type 3 declared eradicated
Today, on World Polio Day, wild poliovirus type 3 has been declared eradicated by a commission of the World Health Organization. The last case of type 3 poliomyelitis was recorded in 2012 in Nigeria. Because wild poliovirus type 2 was declared eradicated in 2015, now only wild poliovirus type 1 continues to circulate, causing paralysis …
TWiV 567: Outbreaks and a breakout
The TWiV team covers outbreaks of eastern equine encephalitis virus in the US and poliovirus in the Philippines, and explain how a chemokine induced by HIV-1 infection helps release more virus particles from cells. Click arrow to play Download TWiV 567 (68 MB .mp3, 112 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv
Polio returns to the Philippines
Cases of poliomyelitis have been reported in the Philippines 19 years after the country was declared free of the disease. The return of poliomyelitis to the country emphasizes the need to maintain high levels of immunization while polioviruses continue to circulate.
A test of the poliovirus endgame
The global withdrawal of the Sabin type 2 poliovirus vaccine is a test of the feasibility of the plan, declared by the World Health Assembly in 1988, to eradicate all polioviruses.