norovirus

A Pill to Prevent Gastroenteritis

by Gertrud U. Rey Norovirus is the most common food-borne virus and the leading cause of gastroenteritis globally. Despite an urgent need, there are currently no licensed vaccines to prevent norovirus-induced illness. Nevertheless, recent developments in this field have led to remarkable and promising new advances. A phase 1b clinical trial has revealed that a …

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Transmission of Enteric Viruses through Saliva

by Gertrud U. Rey Norovirus and rotavirus are considered to be enteric pathogens because they are traditionally thought to be transmitted by the fecal-oral route; i.e., when consuming food prepared by someone who did not wash their hands properly after using the bathroom. Unlike rabies virus, which replicates in the salivary glands and transmits through …

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TWiV 513: Double-stranded in Belgium

From the 13th International Symposium on dsRNA viruses in Belgium, Vincent speaks with Harry Greenberg about his career and his work on rotaviruses, noroviruses, hepatitis B virus, and influenza virus. <span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”></span>&lt;span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”&gt;&lt;/span&gt;&lt;span data-mce-type=”bookmark” style=”display: inline-block; width: …

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TWiV 493: Condit is on drugs and norovirus is lit

The TWiVerati discuss the FDA Advisory Committee deliberation on the anti-poxvirus drug tecovirimat, and immune cells in gut-associated lymphoid tissue as the major target during acute murine norovirus infection. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler <span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”></span>&lt;span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: …

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TWiV 491: The Ileum and the Odyssey

The TWiVome deconstructs the evolutionary history of RNA viruses, and immune promotion of murine norovirus pathogenesis by replication in intestinal tuft cells. <span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”></span>&lt;span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”&gt;&lt;/span&gt;&amp;lt;span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”&amp;gt;&amp;lt;/span&amp;gt;&amp;amp;lt;span data-mce-type=”bookmark” style=”display: …

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