neuron

Neurotropism of enterovirus D68 is not a recently acquired property

Basic virology, Information / By

with Amy Rosenfeld Enterovirus D68 (EV-D68) was first isolated from children with respiratory disease in 1962. No outbreaks of infection were detected until the late summer and early fall of 2014, and then in 2016 and 2018. During these epidemics of respiratory disease, some children developed polio-like paralysis. We have recently published a paper showing …

Neurotropism of enterovirus D68 is not a recently acquired property Read More »

TWiV 477: Raiders of the lost Arc

This Week in Virology / By

The TWiVodrome explains how a gag-like protein from a retrotransposon forms virus-like particles that carry mRNA within vesicles across the synapse. <span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”></span>&lt;span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”&gt;&lt;/span&gt;&amp;lt;span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”&amp;gt;&amp;lt;/span&amp;gt; Click arrow to …

TWiV 477: Raiders of the lost Arc Read More »

How prions make you sick

2 Comments / Basic virology, Information / By

Transmissible spongiform encephalopathies (TSEs) are rare, but always fatal, neurodegenerative disorders of humans and other mammals. They are characterized by long incubation periods, spongiform changes in the brain associated with loss of neurons, and the absence of host responses. TSEs are caused by infectious proteins called prions. Insight into how prions cause TSEs comes from the observation that …

How prions make you sick Read More »

TWiV 378: Herpes plays DUBstep

1 Comment / This Week in Virology / By

On episode #378 of the science show This Week in Virology, Greg Smith joins the TWiVirate to reveal how his lab discovered a switch that controls herpesvirus neuroinvasion, and then we visit the week’s news about Zika virus. You can find TWiV #378 at microbe.tv/twiv, or you may listen below. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV378.mp3″] Click arrow to play Download TWiV …

TWiV 378: Herpes plays DUBstep Read More »

Poliovirus

3 Comments / Information / By

Poliovirus is the etiologic agent of the paralytic disease known as poliomyelitis. It’s also the virus I’ve worked on for most of my career. The World Health Organization is in the midst of a massive effort to eradicate the disease, an undertaking that has encountered a number of obstacles. In coming posts I’d like to …

Poliovirus Read More »

Scroll to Top