Viruses of protozoan parasites may exacerbate human disease

Many protozoan parasites (Trichomonas, Leishmania, Giardia, Plasmodium, Entamoeba, Nagleria, Eimeria, Cryptosporidium) are infected with viruses. These viruses do not infect vertebrates, but their double-stranded RNA genomes are sensed by the innate immune system, leading to inflammatory complications of protozoan infections. Trichomonas vaginalis is a protozoan parasite that infects the genitourinary tract of ~250 million individuals …

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