On episode #331 of the science show This Week in Virology, the TWiV team discusses the possible association of the respiratory pathogen enterovirus D68 with neurological disease. You can find TWiV #331 at www.microbe.tv/twiv.
Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Stephen Goff Retrovirologist Stephen Goff joins Vincent, Rich, and Alan for a discussion of recent papers on the retrovirus XMRV and its association with chronic fatigue syndrome and prostate cancer. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV136.mp3″] Click the arrow above to play, or right-click to download TWiV #136 (61 MB .mp3, 84 minutes). …
Since the first association of the retrovirus XMRV with chronic fatigue syndrome in 2009 in the US, subsequent studies have failed to detect evidence of infection in patients from the US, Europe, and China. These studies were potentially compromised by a number of factors, such as differences in patient characterization, geographic locations, clinical samples used, …
Ila Singh finds no XMRV in patients with chronic fatigue syndrome Read More »
Hosts: Vincent Racaniello, Alan Dove, and Rich Condit On episode #123 of the podcast This Week in Virology, Vincent, Alan, and Rich talk about XMRV integration sites in prostate tumor DNA, the decline effect and scientific method, and the first virus of Caenorhabditis nematodes. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV123.mp3″] Click the arrow above to play, or right-click to download TWiV #123 …
TWiV 123: Contaminated prostates, absolute truth, and bleached worms Read More »
Integration of retroviral DNA into the cellular genome is essential for the production of new infectious particles. A strong argument that the novel human retrovirus XMRV is not a laboratory contaminant is the finding that viral DNA is integrated in chromosomal DNA of prostate tumors. Nucleotide sequence analyses of 14 integration sites in prostate tumor DNAs …
The first detailed study of infection of nonhuman primates with the retrovirus XMRV reveals that the virus establishes a persistent infection characterized by infection of multiple tissues. Viremia (virus in the blood) is low and transient, with proviral DNA detectable in blood lymphocytes. The results show that the Rhesus macaque can be used to study …
