influenza

TWiV 112: Creating a killer poxvirus

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit On episode #112 of the podcast This Week in Virology, Vincent, Alan, and Rich review the making of a virulent poxvirus by insertion of the gene encoding IL-4, and severe 2009 H1N1 influenza due to pathogenic immune complexes. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV112.mp3″] Click the arrow above to play, or right-click to …

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Pandemic influenza vaccine was too late in 2009

Influenza researcher Peter Palese visited yesterday and spoke about “Pandemic influenza: Past and Future”. A key part of his talk was a review of his efforts to produce a universal influenza vaccine which protects against all strains. He used the following graph to make the point that when influenza pandemic strains emerge, there is insufficient …

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TWiV 107: Warning – this virus contains email

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Rich Condit On episode #107 of the podcast This Week in Virology, Vincent, Dickson, Alan, and Rich answer listener questions about poliovirus, social media, dengue, influenza, evolution, gel filtration, and much more. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV107.mp3″] Click the arrow above to play, or right-click to download TWiV #107 (68 MB …

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Thoughts on this season’s influenza vaccine

After my lecture on influenza pathogenesis and evolution at the Northeast Laboratory Conference 2010 in Portland, Maine, I was asked if it is necessary to receive the influenza vaccine every year. This question was precipitated by my statement that the 2010-11 trivalent influenza vaccine contains the same swine-origin H1N1 strain as last year€™s monovalent vaccine. …

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TWiV 103: Shots with LJ Tan

Hosts: Vincent Racaniello, Alan Dove, and LJ Tan On Episode 103 of the podcast This Week in Virology, Vincent and Alan discuss influenza vaccines with LJ Tan of the American Medical Association. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV103.mp3″] Click the arrow above to play, or right-click to download TWiV #103 (56 MB .mp3, 77 minutes) Subscribe to TWiV (free) in …

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Universal influenza vaccines

The need to re-formulate the influenza virus vaccine in response to viral antigenic drift and shift makes for complex logistics of vaccine production and administration. Surveillance programs must be conducted each year to identify strains that are likely to predominate and cause disease. Wouldn€™t it be simpler if a single vaccine could be developed that …

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