inflammation

TWiV 834: COVID-19 clinical update #90 with Dr. Daniel Griffin

This Week in Virology / By Vincent Racaniello

In COVID-19 clinical update #90, Dr. Griffin covers FDA expansion for booster doses, 3 more at home antigen tests approved by FDA, immune correlates analysis of mRNA-1273 vaccine, risk for stillbirth, PROVENT prophylaxis trial results, fluvoxamine recommendations, advice on molnupiravir, automated text messaging service for monitoring illness, and long COVID-19 after vaccination and infection. Click …

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TWiV 831: COVID-19 clinical update #89 with Dr. Daniel Griffin

This Week in Virology / By Vincent Racaniello

In COVID-19 clinical update #89, Dr. Griffin reviews upcoming meeting on FDA emergency use authorization for molnupiravir, 25% of US cases in children, reinfection associates with presence of antibodies, national surveillance for acute flaccid myelitis in the US, and monoclonal antibody treatment of infection in vaccinated, high-risk individuals. Click arrow to playDownload TWiV 831 (20 MB .mp3, …

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TWiV 828: COVID-19 clinical update #88 with Dr. Daniel Griffin

This Week in Virology / By Vincent Racaniello

In COVID-19 clinical update #88, Dr. Griffin covers vaccine protection among US veterans, absence of long COVID in vaccinated who are infected, single dose of REGEN-COV monoclonal antibody cocktail provides long term protection, and Pfizer protease inhibitor Paxlovid is 89% effective in preventing hospitalization or death. Show notes at microbe.tv/twiv

Red blood cells are immune sentinels

Immune, Information / By Vincent Racaniello

Did you know that the innate immune DNA sensor TLR9 is on the membrane of red blood cells? I didn’t know that. To learn about why it’s there, listen to Immune episode #50. In that episode we review evidence that toll-like receptor 9 on the surface of red blood cells binds DNA, leading to uptake …

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TWiV 561: Hot or not

1 Comment / This Week in Virology / By Vincent Racaniello

The Autonomous CollecTWiVe reveal two effective treatments for Ebolavirus infection, how a virus in a fungus confers heat tolerance to a plant, and dampened inflammation as a mechanism for bat tolerance to viral infection. Click arrow to play Download TWiV 561 (57 MB .mp3, 93 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv

Viruses and autoimmunity

1 Comment / Basic virology, Gertrud Rey / By Gertrud U. Rey

by Gertrud U. Rey Type 1 diabetes is an organ-specific autoimmune disease that is characterized by the loss of insulin-producing beta cells in the pancreas. The loss of these cells leads to decreased insulin production (hypoinsulinemia) and increased levels of glucose in the blood (hyperglycemia). While it is still unclear what exactly causes the loss …

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