TWiEVO 79: When the immune system is away, SARS-CoV-2 will play
Nels and Vincent discuss an analysis of the drivers of evolution of SARS-CoV-2 during chronic infections, indicating that a tradeoff exists between antibody evasion and fitness.
immunocompromised
TWiV 676: Tragic gene flow from Neanderthals
In this episode we explain how regions of the human genome associated with severe COVID-19 are identified, the finding that one of these regions was inherited from Neanderthals, and prolonged SARS-CoV-2 reproduction in an immunocompromised patient.
TWiV 520: This old mouse
The TWiVidae review universal influenza vaccines that are in clinical trials, and discovery of an atypical parvovirus that causes chronic kidney disease in middle aged, immunocompromised laboratory mice. <span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”></span> Click arrow to play Download TWiV 520 (70 MB .mp3, 116 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show …