by Gertrud U. Rey It is well known that stress and exposure to UV radiation can reactivate replication of latent herpes simplex virus type 1 and/or type 2 (HSV-1 and/or HSV-2), and the painful lesions associated with these infections. But why is that? During a primary infection, HSV-1 and HSV-2 replicate within the epithelial cells …
HSV-1 virions capture the cellular motor protein kinesin from initially infected epithelial cells and ferry it to subsequently infected neuronal cells to deliver their genome into the nucleus of those cells.
The TWiVomers review a potential role for herpes simplex virus type 1 as a cause of Alzheimer’s Disease, including the finding that amyloid-beta acts as an antiviral by enveloping virus particles.  Click arrow to play Download TWiV 519 (58 MB .mp3, 96 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv
