by Gertrud U. Rey In recent years, the phrase “gain of function” and its abbreviation “GoF” have attained a sinister connotation that is coupled with a general mistrust toward scientists who engage in this type of experimentation. This public perception is grounded in a basic misunderstanding of what constitutes GoF and a lack of appreciation …
Elke, Adam, and Gabor join TWiV to discuss their work on Lloviu virus, a filovirus, including recovery of infectious virus from a DNA copy of the genome and from Schreiber’s bats in Hungary.
TWiV explores the impact of the intestinal virome on seroconversion after rotavirus vaccination, and implications of the ability of the SARS-CoV-2 beta variant to infect wild-type laboratory mice. Click arrow to playDownload TWiV 846 (61 MB .mp3, 102 min)Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv
TWiV minus one reveals delayed neurological deficits in children without microcephaly born to Zika virus infected mothers, and N-glycolyl-neuraminic acid as a receptor for influenza A viruses. Click arrow to play Download TWiV 556 (62 MB .mp3, 103 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv
The TWiVers discuss the spread of African swine fever virus and its threat to pig farming, and the zoonotic potential of peste des petits ruminants virus. Click arrow to play Download TWiV 532 (60 MB .mp3, 99 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv
Measles virus does not just cause a rash – it can kill, up to 100,000 people each year. And there are many related viruses circulating in other animals that are not far from being able to infect human cells.