Fragments of an abundant protein produced by the prostate form amyloid fibrils that enhance infection of cells by human immunodeficiency virus type 1. These fibrils, called semen-derived enhancer of virus infection (SEVI), have been found to boost infection of prostate cells by the retrovirus XMRV. Is this evidence that XMRV causes prostate cancer? Because most …
XMRV infection is enhanced by prostatic protein fragments Read More »
Hosts: Vincent Racaniello, Alan Dove, and Marc Pelletier Vincent, Alan, and Marc talk about chronic wasting disease of deer caused by prions, blocking the semen-derived enhancer of HIV infection with surfen, and making green transgenic rabbits using a lentiviral vector. This episode is sponsored by Data Robotics Inc. Use the promotion code VINCENT to receive …
Hosts: Vincent Racaniello and Dickson Despommier Vincent and Dickson continue virology 101 with a discussion of information flow from RNA to DNA, a process known as reverse transcription, which occurs in cells infected with retroviruses, hepatitis B virus, cauliflower mosaic virus, foamy viruses, and even in uninfected cells. This episode is sponsored by Data Robotics …
Hosts: Vincent Racaniello, Alan Dove, and Rich Condit Vincent, Alan, and Rich discuss ten compelling virology stories of 2009. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV064.mp3″] Click the arrow above to play, or right-click to download TWiV #64 (68 MB .mp3, 94 minutes) Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by …
In the summer of 1989, two papers about viruses were published in high-profile journals. One described the engineering of a recombinant poliovirus bearing on its surface an antigen from HIV-1. The second paper claimed that transgenic mice could be made by adding DNA to sperm before using them to fertilize eggs. Both reports played a …
Viruses and journalism: Poliovirus, HIV, and sperm Read More »
Hosts: Vincent Racaniello, Dickson Despommier, and Alan Dove On episode #62 of the podcast This Week in Virology, Vincent, Dickson, and Alan discuss STEP HIV-1 vaccine failure caused by the adenovirus vector, presence of West Nile virus in kidneys for years after initial infection, adaptation of the influenza viral RNA polymerase for replication in human …
