HIV-1

Dogma Does Not Belong in Science

by Gertrud U. Rey According to established scientific dogma, infection of cells with HIV-1 leads to delivery of the viral capsid into the cell cytoplasm, followed by “uncoating” of the capsid to release the single-stranded RNA genome. A viral-encoded enzyme called reverse transcriptase then catalyzes the conversion of the viral RNA into a single strand …

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How the Viruses Within Us Protect Us From Other Viruses

by Gertrud U. Rey Did you know that eight percent of the human genome consists of DNA sequences that are derived from retroviruses? These “endogenous retroviruses” (ERVs) represent concrete evidence for retroviral infections that occurred in our ancestors. Although ERVs have no viral activity, an accumulating body of evidence suggests that they are not entirely …

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TWiV 639: Virology Nobel Prizes with Erling Norrby part 2

Vincent and Erling resume their discussion of virology Nobel Prizes, focusing on awards for research on tumor viruses, bacteriophages, virus structure, reverse transcriptase, hepatitis B virus, HIV-1, human papillomaviruses and much more. Click arrow to playDownload TWiV 639 (65 MB .mp3, 108 min)Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv

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