Team TWiV reveals DNA polymerases that do not require a primer, and packaging of hepatitis delta virus by the envelope glycoproteins of diverse viruses. Click arrow to play Download TWiV 552 (70 MB .mp3, 116 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv
Hepatitis D virus is a unique human pathogen. With a circular, negative stranded RNA genome of ~1700 nucleotides, it is the smallest known human virus. Formation of the HDV particle depends on co-infection of cells with a helper virus, hepatitis B virus. Once thought to be specific for humans, related viruses have now been identified …
On episode #210 of the science show This Week in Virology, the complete TWiV team reviews identification of the cell receptor for hepatitis B and D viruses, and the cell enzyme that cleaves the genome-linked protein from picornaviral RNA. You can find TWiV #210 at www.microbe.tv/twiv.
Download: .wmv (350 MB) | .mp4 (96 MB) Visit the virology W3310 home page for a complete list of course resources.
