evolution

TWiEVO 56: Revising the drafts of coronavirus evolution

Nels and Vincent continue their discussion of SARS-CoV-2 evolution, including understanding recurrent mutations in the viral genome, and the potential for re-emergence of the virus from an animal reservoir. Click arrow to play Download TWiEVO 56 (53 MB .mp3, 88 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiEVO Show notes at microbe.tv/twievo

TWiEVO 55: Coronavirus evolution from soup to nuts

Nels and Vincent continue their discussion of SARS-CoV-2 evolution, with a report that the coronavirus proofreading enzyme stimulates RNA recombination, and debunking the conclusion that a change in the viral spike glycoprotein is associated with increased human to human transmission. Click arrow to play Download TWiEVO 55 (45 MB .mp3, 74 min) Subscribe (free): iTunes, Google Podcasts, RSS, email …

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TWiV 588: Coronavirus update – Save the pangolin!

The TWiV team returns this week to SARS-CoV-2019 coverage to review the latest epi curves, the fatality rate, furin cleavage site and receptor binding domain in the spike glycoprotein, related CoV recovered from pangolins, evidence that the virus did not escape from a laboratory, and many more questions sent in by listeners. Click arrow to …

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Rabbits and viruses: An iconic example of natural selection

When viruses are introduced into a new population, selection pressures can lead to evolution of both pathogen and host. The pathogen must adapt to a new host, while the latter can become resistant to infection, leading to an arms race. An archetypal example of such host-pathogen evolution is illustrated by the attempt to control rabbit …

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