enteric nervous system

TWiV 527: City mouse, country mouse

The TWiV team summarizes the discovery of Sin Nombre virus, and presents evidence that neurotropic flaviviruses can cause intestinal dysmotility syndromes after systemic infection of mice. <span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”></span>&lt;span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”&gt;&lt;/span&gt;&amp;lt;span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: …

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Viral infections of the enteric nervous system and intestinal dysmotility

Intestinal dysmotility disorders such as irritable bowel syndrome affect 10-30% of humans in Western countries. Some of these diseases appear to correlate with viral infection. Inoculation of mice with neurotropic flaviviruses leads to injury and death of enteric neurons, inflammation, intestinal dilation and retarded bowel transit, providing a model for studying and treating these human …

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