ebolavirus

TWiV 394: Cards in a hand

Vincent and Alan speak with Erica Ollmann Saphire about her career and her work on understanding the functions of proteins of Ebolaviruses, Marburg virus, and other hemorrhagic fever viruses, at ASM Microbe 2016 in Boston, MA. You can find TWiV #394 at microbe.tv/twiv, or listen or watch the video below. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV394.mp3″] Click arrow to …

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A promising Ebolavirus antiviral compound

A small molecule antiviral compound has been shown to protect rhesus monkeys against lethal Ebolavirus disease, even when given up to three days after virus inoculation. The compound, called GS-5734, is a nucleoside analog. After uptake into cells, GS-5734 is converted to a nucleoside triphosphate (illustrated, bottom panel) which is incorporated by the viral RNA dependent RNA …

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TWiEVO

TWiEVO 5: Looking at straw colored fruit bats through a straw

On episode #5 of the science show This Week in Evolution, Sara Sawyer and Kartik Chandran join Nels and Vincent to talk about how the filovirus receptor NPC1 regulates Ebolavirus susceptibility in bats. You can find TWiEVO #5 at microbe.tv/twievo, or you can listen below. [powerpress url=”http://traffic.libsyn.com/twievo/TWiEVO005.mp3″] Click arrow to play Download TWiEVO 5 (73 MB .mp3, 98 min) Subscribe (free): iTunes, RSS, email

Zika from sex, the byway but not the highway

Can Zika virus be sexually transmitted? Perhaps in very rare cases, but the main mode of transmission is certainly via mosquitoes. That’s why I’ve shamelessly stolen a quote on this topic from Dr. William Schaffner of Vanderbilt University: Mosquito transmission is the highway, whereas sexual transmission is the byway. Sexual transmission cannot account for this …

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