Ebola

An antiviral for enveloped viruses

Broad spectrum antibiotics are available that act against a wide range of bacteria, including both gram-positive and gram-negative species. In contrast, our antiviral arsenal is exceedingly specific. Nearly all the known antivirals block infection with one or two different viruses. The discovery of a compound that blocks infection with many different enveloped viruses may change …

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TWiV 47: Vertical vaccine farm

Hosts: Vincent Racaniello and Dick Despommier On episode #47 of the podcast “This Week in Virology”, Vincent and Dick discuss influenza virus-like particle vaccines produced in insect and plant cells, rapid sharing of influenza research, and answer listener questions about cytomegalovirus, viral evolution and symbiosis and much more. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV047.mp3″] Click the arrow above to …

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TWiV #25: Viral evolution

In episode #25 of the podcast This Week in Virology, Vincent, Alan, and Luis Villarreal talk about rabies in Viet Nam and Angola, needle-stick infections with ebolavirus and West Nile virus, and viral evolution. Click the arrow above to play, or right-click to download TWiV #25 or subscribe in iTunes or by email.

Ebola virus glycoprotein antagonizes tetherin

The innate response to virus infection is a marvel: when confronted with an invading microbe, it responds rapidly by producing interferons and other cytokines which establish an antiviral state. Its effectiveness is underscored by the fact that every viral genome must encode countermeasures that modulate its activity. A recent paper in PNAS adds another mechanism …

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TWiV #18: Can a virus make you fat?

On This Week in Virology #18, Vincent, Dick, and Alan discuss adenovirus type 36 and obesity, new influenza antiviral drugs, viral hemorrhagic septicemia virus of fish, and Ebola virus in pigs and pig farmers in the Phillipines. Click the arrow above to play, or right-click to download TWiV #18

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