When it comes to safeguarding the health of the US, there is no one I trust more than Dr. Anthony Fauci, head of NIAHD/NIH (whom I was fortunate to interview on TWiV in 2013). So when Dr. Fauci says that 100,000 people could die in the SARS-CoV-2 outbreak just in the US, I take notice. …
How many deaths caused by SARS-CoV-2 will there be in the US? Read More »
Ralph Baric joins TWiV to dissect the coronavirus pandemic caused by SARS-CoV-2, including discussion on community spread, asymptomatic infections, origin of the virus, transmission, vaccine development, and much more. Click arrow to play Download TWiV 591 (75 MB .mp3, 123 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv
Driving the anxiety and uncertainty about the current outbreak of COVID-19 is the case fatality ratio (CFR) being thrown about carelessly by not just the press, but also WHO and other organizations. However the CFR is not a one-size-fits all, and is influenced by many factors.
When virologists Fouchier and Kawaoka were isolating avian influenza H5N1 viruses that could transmit among ferrets by aerosol, there was consternation from some quarters that such viruses might escape from the laboratory and cause a pandemic in humans. Part of the fear came from the fact that the case fatality ratio for human infections with …
Incidence of asymptomatic human influenza A(H5N1) virus infection Read More »
When I am asked to name the most lethal human virus, I never hesitate to name rabies virus. Infection with this virus is almost invariably fatal; just three unvaccinated individuals have been known to survive. New evidence from humans in the Peruvian Amazon suggests that the virus might be less lethal than previously believed. Rabies …
The prominent lead editorial in the New York Times of Sunday, 8 January 2012 is entitled ‘An Engineered Doomsday’. It concerns recent avian influenza H5N1 research, in which scientists in the Netherlands and at the University of Wisconsin found that by passaging the virus in ferrets it could acquire aerosol transmissibility. Let’s determine if the scientific facts …
N.Y. Times: H5N1 ferret research should not have been done Read More »
