Antigenic variation is a hallmark of influenza virus that allows the virus to evade host defenses. Consequently influenza vaccines need to be reformulated frequently to keep up with changing viruses. In contrast, antigenic variation is not a hallmark of poliovirus – the same poliovirus vaccines have been used for nearly 60 years to control infections by …
On episode #257 of the science show This Week in Virology, the TWiV team consider how the kinase mTOR modulates the antibody response to provide broad protection against influenza virus, and explore the problems with scientific research. You can find TWiV #257 at www.microbe.tv/twiv.
On episode #218 of the science show This Week in Virology, Vincent, Alan, and Welkin discuss how endogenous retroviruses in mice are held in check by the immune response. You can find TWiV #218 at www.microbe.tv/twiv.
Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, Alan Dove, and Welkin Johnson Welkin joins the TWiV team for a discussion of HIV prophlaxis using vectored antibodies, and the influenza H5N1 virus studies in ferrets that were not redacted. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV168.mp3″] Click the arrow above to play, or right-click to download TWiV 168 (59 MB .mp3, 98 minutes). …
TWiV 168: Super CalTech prophylaxis and ferret runny noses Read More »
Hosts: Vincent Racaniello, Rich Condit, Alan Dove, and Gabriel Victora Vincent, Rich, Alan and Gabriel review the production of antibodies by B cells, and how high affinity antibodies are selected in the germinal centers of lymph nodes. Please help us by taking our listener survey. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV161.mp3″] Click the arrow above to play, or right-click to download …
The bacteria in our intestines outnumber by tenfold the 100 trillion cells that comprise the human body. This gut microbiota has many beneficial functions, including the production of vitamins and hormones, fermentation, regulation of gut development, and shaping intestinal immune responses. They also play a role in pathological conditions such as diabetes and obesity, and …
Gut microbes influence defense against influenza Read More »
