amyloid plaque

TWiV 519: Fishing for viruses in senile

This Week in Virology / By

The TWiVomers review a potential role for herpes simplex virus type 1 as a cause of Alzheimer’s Disease, including the finding that amyloid-beta acts as an antiviral by enveloping virus particles.  Click arrow to play Download TWiV 519 (58 MB .mp3, 96 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv

Herpes simplex virus and Alzheimer€™s disease

1 Comment / Basic virology, Commentary, Information / By

Alois Alzheimer was the first to propose that an infection might play a role in the disease named after him. Herpes simplex virus type 1 (HSV-1) has been most frequently linked to Alzheimer€™s Disease (AD), and a clinical trial is in progress to determine if antivirals ameliorate its development. What is the evidence that HSV-1 …

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