Influenza virus in the eye
…the human eye. Infection of these cultures with both ocular and non-ocular tropic viruses showed that ocular tropic viruses infect eye cells more efficiently than do non-ocular tropic viruses. In…
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Complementing neutralization of viruses by antibodies
…activates proteases that cleave C4 to form C4b. The latter protein is chemically reactive and binds to the nearby adenovirus capsid. Binding of C4b to the adenovirus capsid prevents the…
Why do we still use Sabin poliovirus vaccine?
…three serotypes of poliovirus by passage of virulent viruses in different animals and cells. In contrast to Theiler’s yellow fever vaccine, which was injected, Sabin’s poliovirus vaccines were designed to…
An epidemic of porcine diarrhea in North America
…The coronavirus family is divided into four genera: Alphacoronavirus, Betacoronavirus, Gammacoronavirus and Deltacoronavirus. Several human coronaviruses that cause common cold-like illness, as well as PEDV, are alphacoronaviruses. SARS-CoV and MERS-CoV…
Increased fidelity reduces viral fitness
We have spent over a week discussing the effects of polymerase error rates on viruses. RNA viruses have the highest error rates in nature, a property that is believed to…
Influenza virus in the toilet
…in the near future. I have no doubt that Clorox Toilet Bowl Cleaner will inactivate influenza virus (viruses cannot be killed, as they are not living). The active ingredient is…