Influenza HA cleavage is required for infectivity
The influenza virus hemagglutinin (HA) is the viral protein that attaches to cell receptors. The HA also plays an important role in the release of the viral RNA into the…
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Influenza A/Mexico/2009 (H1N1) – Questions and answers
Here are answers to questions send to virology blog about the new strain of influenza H1N1 that is spreading globally. Q: Regarding this marker (PB1-F2) – is it something that…
TWiV 950: Prion diseases with Richard Knight
From the European Society for Clinical Virology 2022 Conference in Manchester UK, Vincent speaks with Richard Knight about prion diseases and the outbreak of bovine spongiform encephalitis that led to cases…
Infectious DNA clones
The development of recombinant DNA methods by Cohen and Boyer in 1973, together with the discovery of reverse transcriptase by Temin and Baltimore in 1970, made it possible to introduce…
D. Carleton Gajdusek, 85
Virologist D. Carleton Gajdusek, who was awarded the 1976 Nobel Prize in medicine for unraveling the nature of the prion disease Kuru, has died, as reported by the New York…
Resistance to prion disease in humans
Transmissible spongiform encephalopathies (TSEs) are rare human neurodegenerative disorders that are caused by infectious proteins called prions. A naturally occurring variant of the human prion has been found that completely…