The risks and benefits of influenza H5N1 research
…on influenza H5N1 transmission did not make the virus more dangerous – they made it less dangerous for ferrets. How they affect the virus in humans is unknown. I suspect…
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A lesson from SARS-CoV for 2019-nCoV
As with all previous outbreaks of new virus infections, we are being warned of impending doom concerning the new coronavirus, 2019-nCoV that is now spreading globally. China€™s National Health Commission…
Avian influenza H7N7 virus outbreak: Lessons for H7N9
…influenza H7N9 viruses in China. During the Dutch outbreak 453 humans showed symptoms of illness and 89 were confirmed to have infection with the virus. Some interesting observations from that…
XMRV infection is enhanced by prostatic protein fragments
…Fibrils of Prostatic Acid Phosphatase Fragments Boost Infections with XMRV (Xenotropic Murine Leukemia Virus-Related Virus), a Human Retrovirus Associated with Prostate Cancer Journal of Virology, 83 (14), 6995-7003 DOI: 10.1128/JVI.00268-09…
Defective viral genomes and severe influenza
…more lethal viruses that produce low levels of defective genomes, the consequence is that the virus is able to replicate to higher titers in the host. In turn, higher virus…
Furin cleavage site in the SARS-CoV-2 coronavirus glycoprotein
…the coronavirus. The MERS-CoV S glycoprotein contains a furin cleavage site and is probably processed by these intracellular proteases during exit from the cell. The virus particles are therefore ready…