TWiV 654: TWiVering with excitement

Daniel Griffin provides a clinical report on COVID-19 and the convalescent plasma trial, then we answer listener questions about the Russian vaccine, choir practice, face masks (wear them!), Mina testing, transmission, and much more. Click arrow to playDownload TWiV 654 (93 MB .mp3, 156 min)Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv

TWiV 653: Back to school with COVID-19

Alfonso, Ken, Mary and Janet join TWiV to explain their modeling of school reopening strategies during the SARS-CoV-2 pandemic. Click arrow to playDownload TWiV 653 (34 MB .mp3, 56 min)Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv

The future of SARS-CoV-2

What does the future hold for SARS-CoV-2? Will it remain in its current configuration, with 20% of infections causing serious damage? Will everyone on Earth need to be vaccinated regularly to prevent infection? Allow me to indulge in some speculation and suggest that SARS-CoV-2 will eventually become the fifth common cold coronavirus (CoV). There are …

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TWiV 652: The rules of contagion with Adam Kucharski

Epidemiologist Adam Kucharski joins TWiV to discuss SARS-CoV-2, including R0, incubation period, herd immunity, asymptomatic infection, superspreaders, children as drivers of pandemics, and how this one will end. Click arrow to playDownload TWiV 652 (69 MB .mp3, 114 min)Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv

TWiN 9: COVID-19 neurology with Genna Waldman

Columbia University Chief Neurology Resident Genna Waldman joins TWiN to explains how her department prepared for COVID-19, and the neurological symptoms associated with the disease. Click arrow to playDownload TWiN 009  (40 MB .mp3, 67 min)Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiN! Show notes at microbe.tv/twin

TWiV 651: FDA rules with Denise Esposito

Daniel Griffin provides a clinical report on COVID-19, then former FDA Chief of Staff to the Commissioner Denise Esposito joins us to explain the challenges in approving vaccines, antiviral drugs, and diagnostic tests during a pandemic, followed by answers to listener questions. Click arrow to playDownload TWiV 651 (98 MB .mp3, 164 min)Subscribe (free): iTunes, Google Podcasts, RSS, email Become …

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Trial By Error: New Paper Seeks to Reframe Poor Findings in CODES Trial of CBT for Non-Epileptic Seizures

By David Tuller, DrPH The CODES trial investigated cognitive behavior therapy (CBT) as a treatment for dissociative seizures (DS), a sub-category of what is now called functional neurological disorder (FND). The intervention was a course of CBT specifically designed to address the variety of factors presumed to be triggering the seizures. (I have previously critiqued …

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Trial By Error: Professor Edwards’ Take on Nutrition and Severe ME Cases

By David Tuller, DrPH Jonathan Edwards, a professor emeritus of medicine at University College London, has released a document involving the provision of care for people with severe ME, an issue at the core of some recent high-profile cases in England. The document, which Professor Edwards posted on a pre-print server, is called “Management of …

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Trial By Error: The Conversation Recycles Biopsychosocial Nonsense

By David Tuller, DrPH A new piece in The Conversation shows just how problematic it is when poorly done biopsychosocial studies claim to have documented that cognitive and/or behavioral therapies are effective—and when these questionable findings are published in high-impact journals. The headline of the article: “Success in treating persistent pain now offers hope for …

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Trial By Error: Some Things I Read This Week–Scathing “Effort Preference” Analysis; Kids with Long Covid; National Academies’ Long Covid Definition

By David Tuller, DrPH An in-depth pushback on “effort preference” When the U.S. National Institutes of Health’s long-delayed “deep phenotyping” study of a handful of ME/CFS patients was released earlier this year, the focus on a weird construct called “effort preference” sucked up all the attention–in part because the paper placed it front and center, …

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Trial By Error: Athlete Oonagh Cousins on the Lightning Process

By David Tuller, DrPH Oonagh Cousins, a world-class rower who once dreamed of representing Great Britain in the Olympics, got sick early in the pandemic and has been suffering from Long Covid ever since. Her story was first covered by the BBC in November, 2020. A BBC article last year covered how her condition had …

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Trial By Error: Betsy Ladyzhets on Problems with NIH’s RECOVER Initiative

By David Tuller, DrPH Science journalist Betsy Ladyzhets, co-founder and co-editor of The Sick Times, has been covering the problemls with RECOVER, the $1.15 billion Long Covid initiative from the US National Institutes of Health. Ladyzhets recently wrote a new article about RECOVER, published in The Sick Times as well as STAT, based on documents …

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