David Tuller

Trial By Error: Some More Thoughts on Functional Neurological Disorder

By David Tuller, DrPH Last week I wrote a post on some of the signs used to diagnose people with "functional neurological disorder" (FND)--the phrase that has largely supplanted "conversion disorder" to describe neurological symptoms with no identified organic cause. In that post, I should have been clearer that I ...

Trial By Error: My 2011 Exchange with White et al about Case Definition

By David Tuller, DrPH My first exchange of views with the PACE authors involved the issue of case definition--the criteria used to identify the illness they  called chronic fatigue syndrome. This exchange took place courtesy of The New York Times, not long after The Lancet published the results of the ...

Trial By Error: Shaky Evidence for Signs of Functional Neurological Disorders

By David Tuller, DrPH One of my goals next year is to write more about so-called "medically unexplained symptoms," also known as MUS. The term MUS might be useful as a descriptive name for the large category of phenomena that lack a proven pathophysiological pathway. But in the medical literature, ...

Trial By Error: PEM Is Bad and So Is Fukuda, New Study Finds

By David Tuller, DrPH A new study in the Journal of Psychosomatic Research, posted December 16th, has reported that patients with chronic fatigue syndrome who experience major post-exertional malaise have a greater burden of psychological distress than those whose PEM is minimal or non-existent. Of course, this is not surprising. ...

Trial By Error: My STAT Opinion Piece on BMJ and Dr Godlee

By David Tuller, DrPH On Friday, STAT posted my opinion piece about BMJ and the Lightning Process paper--in particular, about BMJ's decision not to retract the paper despite the multiple documented violations of core ethical and methodological principles of medical research. That anti-scientific decision is potentially harmful not only to ...
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