TWiEVO 79: When the immune system is away, SARS-CoV-2 will play
Nels and Vincent discuss an analysis of the drivers of evolution of SARS-CoV-2 during chronic infections, indicating that a tradeoff exists between antibody evasion and fitness.
This Week in Evolution
TWiEVO 57: SARS-CoV-2 receptor binding evolution blooms
Jessie, Allie and Tyler join Nels and Vincent to describe their work on deep mutational scanning of the SARS-CoV-2 receptor binding domain. Click arrow to playDownload TWiEVO 57 (50 MB .mp3, 84 min)Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiEVO Show notes at microbe.tv/twievo
TWiEVO 56: Revising the drafts of coronavirus evolution
Nels and Vincent continue their discussion of SARS-CoV-2 evolution, including understanding recurrent mutations in the viral genome, and the potential for re-emergence of the virus from an animal reservoir. Click arrow to play Download TWiEVO 56 (53 MB .mp3, 88 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiEVO Show notes at microbe.tv/twievo
TWiEVO 55: Coronavirus evolution from soup to nuts
Nels and Vincent continue their discussion of SARS-CoV-2 evolution, with a report that the coronavirus proofreading enzyme stimulates RNA recombination, and debunking the conclusion that a change in the viral spike glycoprotein is associated with increased human to human transmission. Click arrow to play Download TWiEVO 55 (45 MB .mp3, 74 min) Subscribe (free): iTunes, Google Podcasts, RSS, email …
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TWiEVO 49: A giant podcast on giant viruses
Rich joins Nels and Vincent for a debriefing on the 4th Ringberg Symposium on Giant Virus Biology in Tegernsee, Germany. Click arrow to play Download TWiEVO 49 (68 MB .mp3, 113 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiEVO Show notes at microbe.tv/twievo
TWiEVO 31: Virus archaeology, or when the human genome is the junk
Nels and Vincent present ancient hepatitis B virus genome sequences from Bronze Age to Medieval period human remains. <span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”></span><span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”></span>&lt;span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”&gt;&lt;/span&gt;&lt;span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: …
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