ME/CFS

Trial By Error: My Letter to One of Mahana’s Gastroenterology Advisors

By David Tuller, DrPH On its website, Mahana Therapeutics has listed sixteen gastroenterology and psychology advisors from prominent academic and medical institutions. Companies often add such names to their rosters as a way of signaling their significance and their access to great minds. Sometimes these people are compensated; sometimes not. In many instances, these advisors play little …

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Trial By Error: My Letter to Professor Moss-Morris

By David Tuller, DrPH Last week I wrote about the recently announced licensing deal between Mahana Therapeutics and King’s College London. The deal involves a web-based course of cognitive behavior therapy designed to treat irritable bowel syndrome. In a major study, the reported improvements in symptoms among participants in the web-based program were modest at …

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Trial By Error: My FOI Request to King’s College London; My Letter to Mahana Therapeutics

By David Tuller, DrPH Yesterday I sent a freedom-of-information request to King’s College London about the recently announced licensing deal it has with Mahana Therapeutics. The deal involves a web-based CBT program for irritable bowel syndrome, which I have written about here and here. This morning I sent a note to the e-mail address for …

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Trial By Error: My Talk Last October in Oxford (Video)

By David Tuller, DrPH Last October, I gave a talk in Oxford (not AT Oxford) about the dung-heap known as the Lightning Process trial which was published in 2017 in Archives of Disease in Childhood, a BMJ journal. The study’s full name: “Clinical and cost-effectiveness of the Lightning Process in addition to specialist medical care for …

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Trial By Error: The 2018 PACE Reanalysis and the SMC’s Expert Appraisals

By David Tuller, DrPH It has been almost two years since BMC Psychology published a key reanalysis of raw data from the PACE trial. Given the significance of this paper (of which I was the least important of seven co-authors), I figured it wouldn’t hurt to highlight it again. The heroic Alem Matthees, a patient …

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