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The Lazarus virus

There is an excellent question in the comments to “Are all virus particles infectious?“: if the particle-to-PFU ratio for a virus stock is 10,000:1, and I infect 1,000,000 cells with 10,000 particles, how many plaques would I expect to observe? Answering this question provides insight into the particle-to-PFU ratio of viruses. If we take 10,000 particles …

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David and Goliath: How one cytokine may take down influenza

This article was written for extra credit by a student in my virology course. by Alexandra Jacunski Recent research has suggested a new method of flu prevention and treatment: the administration of granulocyte macrophage-colony stimulating factor (GM-CSF) to the lungs of mice significantly reduced flu symptoms and prevented mortality after a lethal dose of influenza virus. …

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Microbiology blogs

If you have ever wanted to read other blogs on microbiology, head over to Cesar Sánchez’ Twisted Bacteria, where he has compiled a list of his 20 favorites. There are even some in French, Spanish, and Slovenian (for those, don’t forget Google Translate). Thanks, Cesar.

Gut microbes influence defense against influenza

The bacteria in our intestines outnumber by tenfold the 100 trillion cells that comprise the human body. This gut microbiota has many beneficial functions, including the production of vitamins and hormones, fermentation, regulation of gut development, and shaping intestinal immune responses. They also play a role in pathological conditions such as diabetes and obesity, and …

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