Hepatitis B virus (HBV, illustrated) is a substantial human pathogen. WHO estimates that there are now 240,000,000 individuals chronically infected with HBV worldwide, of which 25% will die from chronic liver disease or hepatocellular carcinoma. The hepatitis B virus vaccine is highly effective at preventing infection. Because there are no known animal reservoirs of the …
We have been using HeLa cells in my laboratory since 1982, when I arrived at Columbia University Medical Center fresh from postdoctoral work with David Baltimore at MIT. I brought with me a line of HeLa cells and used them for 30 years for our research on viruses. Here is a story of how we …
When virologists Fouchier and Kawaoka were isolating avian influenza H5N1 viruses that could transmit among ferrets by aerosol, there was consternation from some quarters that such viruses might escape from the laboratory and cause a pandemic in humans. Part of the fear came from the fact that the case fatality ratio for human infections with …
Incidence of asymptomatic human influenza A(H5N1) virus infection Read More »
En esta sesión discutiremos como los virus con genoma de DNA replican sus ácidos nucleÃcos. Consideraremos las enzimas y otras proeteÃnas que participan en la sÃntesis del DNA viral y los retos que imponen las distintas topologÃas de los genomas de DNA (DNA linear de cadena sencilla, DNA circular de doble cadena y DNA linear …
Virologia en Español Clase #7 €“ Replicación de Virus con Genoma de DNA Read More »
From Martin Enserink at ScienceInsider: Virologist Ron Fouchier has suffered a loss in a legal battle with the Dutch government over the publication of his controversial H5N1 influenza research. On Friday, a Dutch district court ruled that the government was right to ask Fouchier to obtain an export license before sending two hotly debated papers …
Fouchier vs the Dutch government on influenza H5N1 research Read More »
On episode #251 of the science show This Week in Virology, the complete TWiV crew reviews work on MERS-coronavirus, including serological studies in camels, production of an infectious DNA clone, and identification of an interferon antagonist. You can find TWiV #251 at www.microbe.tv/twiv.
