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Zika virus and the fetus

An epidemic of Zika virus infection began in Brazil in April 2015, and six months later there was a surge in the number of infants born with microcephaly. Confirming that Zika virus causes microcephaly will require much more information than is currently available. So far there have been few isolations of Zika virus RNA from microcephalic fetuses or amniotic fluid. …

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Rubella virus and birth defects

Amidst the fear surrounding Zika virus, remember that there are over 100,000 children born each year with birth defects caused by infection with rubella virus. The virus Rubella virus is a member of the Togaviridae family, which also includes chikungunya virus. The genome is a 9.7 kilobase, positive strand RNA enclosed in a capsid and surrounded by a membrane …

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Scientists, share your Zika virus reagents!

Today I learned that a number of investigators refuse to share their samples of Zika virus with other laboratories. There are countless stories about scientists not sharing reagents because they want to be the first to make a discovery. This behavior allows them to publish first, secure more grant funding, garner invitations to speak at meetings, and generally stroke their egos. This …

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Zika from sex, the byway but not the highway

Can Zika virus be sexually transmitted? Perhaps in very rare cases, but the main mode of transmission is certainly via mosquitoes. That’s why I’ve shamelessly stolen a quote on this topic from Dr. William Schaffner of Vanderbilt University: Mosquito transmission is the highway, whereas sexual transmission is the byway. Sexual transmission cannot account for this …

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Zika virus

The rapid spread of Zika virus through the Americas, together with the association of infection with microcephaly and Guillain-Barre syndrome, have propelled this previously ignored virus into the limelight. What is this virus and where did it come from? History Zika virus was first identified in 1947 in a sentinel monkey that was being used to …

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