The Centers for Disease Control and Prevention (CDC) would like to know what the public feels about the impending H1N1 influenza vaccination program this fall. The agency plans to conduct ten meetings in different parts of the United States to learn if the public would like a massive vaccination campaign, or a reduced effort. The meetings …
CDC wants the public to comment on H1N1 vaccination Read More »
A few weeks ago I asked readers to find the errors in the following statement concerning an experimental influenza vaccine produced by Protein Sciences which involves synthesis of the viral HA protein in insect cells. They warned that the virus could mutate during the southern hemisphere’s flu season before returning north in a more lethal form …
There are two glycoproteins embedded in the influenza viral membrane: the hemagglutinin (HA) and neuraminidase (NA). The NA, shown in yellow in the illustration, is an enzyme that removes sialic acids from the surface of the cell, so that newly formed virions can be released. The NA protein is composed of a box-like head attached …
The antibody response is crucial for preventing many viral infections and may also contribute to resolution of infection. When a vertebrate is infected with a virus, antibodies are produced against many epitopes on multiple virus proteins. A subset of these antibodies can block virus infection by a process that is called neutralization. Antibodies can neutralize viral infectivity …
With the looming prospect of mass immunization against influenza, it’s important to understand how vaccines work. To do this we must have a good understanding of adaptive immune defenses. Today we’ll begin a discussion of the humoral arm of the adaptive immune response – antibodies. Antibodies are large proteins produced by vertebrates that play important …
While most adults cannot name a scientist, the readers of virology blog can identify many of them. I asked readers to spontaneously name just one scientist, and I received 204 responses. Nine of the individuals named were not scientists; that left 195 responses out of 204, indicating that 96% of those who responded could name …
