How XMRV, the new human retrovirus associated with prostate cancer and chronic fatigue syndrome, might be transmitted among humans is unknown. The finding that the virus can be detected in prostate cancer cells, and in prostatic secretions of men with prostate cancer suggests that it could be sexually transmitted. To address this question, the presence …
The World Health Organization has declared the end of the pandemic caused by H1N1 influenza virus. According to Director-General Margaret Chan, The world is no longer in phase 6 of influenza pandemic alert. We are now moving into the post-pandemic period. The new H1N1 virus has largely run its course. As we enter the post-pandemic …
The illustration at left depicts a virion – the infectious particle that is designed for transmission of the nucleic acid genome among hosts or host cells. A virion is not the same as a virus. I define virus as a distinct biological entity with five different characteristics. Others believe that the virus is actually the …
Global fish farming may be the solution to the impending collapse of the commercial fishing industry, but penned fish are susceptible to infectious diseases. Infection with salmon infectious anemia virus, an orthomyxovirus, lead Wal-Mart to stop buying farmed salmon from Chile, the world’s second largest producer of the fish. As a consequence Chilean farmed salmon are …
On TWiV 87 a listener asked us to recommend suitable books for children about microbiology. I have since asked for suggestions on Twitter and Facebook, and have begun to compile the following list. The Invisible ABC’s by Rodney P. Anderson The Magic School Bus #6: The Giant Germ by Anne Capeci A World in a …
The influenza virus neuraminidase (NA) protein is required for virus release from the cell, a property exploited by the antiviral drugs oseltamivir (Tamiflu) and zanamavir (Relenza). During clinical testing of oseltamivir in 2001, some individuals shed drug-resistant viruses with an amino acid change from histidine to tyrosine (H274Y) in NA. Such viruses are not inhibited …
Secondary changes allow spread of oseltamivir resistant influenza virus Read More »
