Virology lecture #10: Transcription and RNA processing
Download: .wmv (331 MB) | .mp4 (71 MB) Presented by guest lecturer Saul Silverstein, Ph.D. Visit the virology W3310 home page for a complete list of course resources.
Basic virology
XMRV not detected in Dutch chronic fatigue patients
The suggestion that the retrovirus XMRV is the etiologic agent of chronic fatigue syndrome (CFS) arose from a study in which the virus was found in 68 of 101 US patients. The virus was not detected in two independent studies of 186 and 170 CFS patients in the United Kingdom. A new Dutch study has also …
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Virology lecture #9: Replication of DNA virus genomes
Download: .wmv (352 MB) | .mp4 (74 MB) Presented by guest lecturer Saul Silverstein, Ph.D. Visit the virology W3310 home page for a complete list of course resources.
Virology lecture #8: Translation
Download: .wmv (298 MB) | .mp4 (65 MB) My apologies for the poor audio in this lecture: I neglected to turn on my lapel mic and the entire session was recorded on the microphone in my laptop – which was across the room. Visit the virology W3310 home page for a complete list of course …
Architecture of a bullet-shaped virus
Since electron micrographs first revealed the bullet-shaped morphology of vesicular stomatitis virus (a virus related to rabies virus), understanding the architecture has been elusive. It was known that the RNA genome is wrapped in a helical structure by the viral nucleocapsid (N) protein, but how this structure was encased by the viral matrix (M) protein …
An antiviral for enveloped viruses
Broad spectrum antibiotics are available that act against a wide range of bacteria, including both gram-positive and gram-negative species. In contrast, our antiviral arsenal is exceedingly specific. Nearly all the known antivirals block infection with one or two different viruses. The discovery of a compound that blocks infection with many different enveloped viruses may change …