Virology lecture #19: Transformation and oncogenesis
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Basic virology
A plant virus that switched to vertebrates
Viruses can be transmitted to completely new host species that they have not previously infected. Usually host defenses stop the infection before any replication and adaptation can take place. On rare occasions, a novel population of viruses arises in the new host. These interspecies infections can sometimes be deduced by sequence analyses, providing a glimpse …
Virology lecture #18: HIV pathogenesis
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Inhibition of XMRV by a weapon of mass deamination
All mammalian genomes contain genes encoding Apobec proteins. Several members of this protein family (the name stands for apolipoprotein B mRNA editing complex) are induced by interferon and are intrinsic antiretroviral proteins. Apobec proteins inhibit the replication of XMRV, a new human retrovirus associated with prostate cancer and chronic fatigue syndrome. During retroviral replication, Apobec …
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Virology lecture #17: Acute infections
Download: .wmv (322 MB) | .mp4 (91 MB) Visit the virology W3310 home page for a complete list of course resources.
Virology lecture #16: Persistent infections
Download: .wmv (331 MB) | .mp4 (68 MB) Presented by guest lecturer Saul Silverstein, Ph.D. Visit the virology W3310 home page for a complete list of course resources.