Basic virology

XMRV in human respiratory tract

An important question about the retrovirus XMRV, which has been implicated in prostate cancer and chronic fatigue syndrome, is where the virus replicates in humans. Such information would provide clues about how infection might be transmitted. To date the virus has been detected in malignant prostate cells and in the peripheral blood mononuclear cells and …

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Google Flu Trends is not accurate

Google Flu Trends uses analysis of large numbers of search queries to track influenza-like illness in a population. The idea is that the frequency of certain queries correlates with the percentage of physician visits in which a patient presents with influenza-like symptoms. Google claims that it can accurately estimate the level of weekly influenza activity …

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Recombination between cellular and viral RNA produces a pathogenic virus

Bovine viral diarrhea virus is an economically important animal pathogen that may cause a fatal gastrointestinal disease in beef and dairy herds. Infection of a fetus with this virus during the first trimester leads to the birth of animals that are persistently infected for life. Some animals remain healthy, while others develop severe mucosal disease. …

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