Basic virology

The risks and benefits of influenza H5N1 research

Both Nature and the New York Times have weighed in on the resumption of influenza H5N1 research. In an editorial from 23 January 2013, Nature opines that “Experiments that make deadly pathogens more dangerous demand the utmost scrutiny”: As several critics point out, the assessments of the relative risks and benefits of such research remain …

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End of moratorium on influenza H5N1 research

In early 2012 influenza virus researchers around the world decided to stop working on highly pathogenic avian influenza H5N1 virus. This decision came after work from the Fouchier and Kawaoka laboratories revealed the isolation of influenza H5N1 strains that can be passed among ferrets by aerosol. The moratorium on influenza H5N1 virus research has now …

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Effectiveness of this season’s influenza vaccine

The Centers for Disease Control and Prevention has released early estimates of the effectiveness of this season’s influenza vaccine in preventing influenza infection. Influenza vaccine effectiveness is assessed each year by the U.S. Influenza Vaccine Effectiveness Network. Patients with acute respiratory infection (ARI) are enrolled in the study; respiratory samples are taken and the presence …

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WHO will switch to type 2 inactivated poliovirus vaccine

The World Health Organization’s campaign to eradicate poliomyelitis made impressive inroads in 2012: only 212 cases were reported, compared with 620 the previous year; moreover, India remained polio-free. The dark side of this story is that as wild polio is eliminated, vaccine-associated poliomyelitis moves in to take its place. The landmark decision by WHO to …

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