The emergence and spread throughout Europe of a SARS-CoV-2 variant, 20E (EU1) in the summer of 2020 illustrates how a virus may become dominant not by increased transmissibility but through travel and lack of effective containment and screening. The SARS-CoV-2 variant 20E (EU1) emerged in Spain in the summer of 2020 and spread to multiple …
Holiday travel explains spread of a SARS-CoV-2 variant Read More »
Infection with some parasitic worms may lead to an impaired immune response against pathogenic infections by other parasites, bacteria, and some viruses.
T cells are the other arm of the adaptive immune response (in addition to B cells) that are essential for clearing virus infections. Most studies of immunity to SARS-CoV-2 infection have focused on antibodies and their ability to neutralize virus infection. The observation that variants of concern are less effectively neutralized by antibodies against ancestral …
Recently isolated coronaviruses from humans in Haiti and Malaysia appear to have originated in pigs and dogs.
Eradication of poliomyelitis appears to be on track: types 2 and 3 polioviruses have been declared eradicated, and in the past 12 months there have been just 338 cases of type 1 polio in Afghanistan and Pakistan. But there have also been 491 cases of polio caused by the type 2 Sabin vaccine. The development …
A genetically stable attenuated poliovirus vaccine Read More »
Early interactions of herpes simplex virus type 1 with the immune system involve both Langerhans cells and a newly characterized dendritic cell. Understanding the dynamics of these initial interactions of the virus with cells of the immune system may result in better strategies for HSV-1/-2 vaccines.
