Author name: Vincent Racaniello

I'm Professor of Microbiology and Immunology at Columbia University in New York. I run a research lab where we study poliovirus, rhinovirus, and other RNA viruses. I also love teaching about viruses - check out virology.ws, microbe.tv, or iTunes University for some of my offerings. I want to be Earth's virology professor.

TWiV 428: Lyse globally, protect locally

The TWiVsters explain how superspreader bacteriophages release intact DNA from infected cells, and the role of astrocytes in protecting the cerebellum from virus infection. You can find TWiV #428 at microbe.tv/twiv, or listen below. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV428.mp3″] Click arrow to play Download TWiV 428 (65 MB .mp3, 108 min) Subscribe (free): iTunes, RSS, email Become a patron of TWiV!

TWiV Special: Vincent Munster on MERS-coronavirus and Ebolavirus

At the Rocky Mountain Laboratory in Hamilton, Montana, Vincent speaks with Vincent Munster about the work of his laboratory on MERS-coronavirus and Ebolaviruses. You can find this TWiV Special at microbe.tv/twiv, or listen below. [powerpress url=”http://traffic.libsyn.com/twiv/TWiVspecialmunster.mp3″] Click arrow to play Download TWiV Special (34 MB .mp3, 56 min) Subscribe (free): iTunes, RSS, email Become a patron of TWiV!

TWiV 427: It was a DURC and UV light

The TWiVoids discuss the March for Science, the GOF moratorium, and a classic virology paper on mapping the gene order for vesicular stomatitis virus. You can find TWiV #427 at microbe.tv/twiv, or listen below. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV427.mp3″] Click arrow to play Download TWiV 427 (59 MB .mp3, 98 min) Subscribe (free): iTunes, RSS, email Become a patron of TWiV!

Prions in bacteria

Bacteria do not develop transmissible spongiform encephalopathies, but they have been found to produce prions – proteins that can adopt alternative conformations with different functions. Prion diseases, a frequent topic on this blog, are caused by misfolding of a normal cellular prion protein (illustrated; image copyright ASM Press). Prion proteins are found in other organisms, where the alternative conformation …

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TWiV 426: I’m Axl, and I’ll be your cervid today

The sages of TWiV explain how chronic wasting disease of cervids could be caused by spontaneous misfolding of prion protein, and the role of the membrane protein Axl in Zika virus entry into cells. You can find TWiV #426 at microbe.tv/twiv, or listen below. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV426.mp3″] Click arrow to play Download TWiV 426 (66 MB .mp3, 110 min) Subscribe …

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