Author name: Vincent Racaniello

I'm Professor of Microbiology and Immunology at Columbia University in New York. I run a research lab where we study poliovirus, rhinovirus, and other RNA viruses. I also love teaching about viruses - check out virology.ws, microbe.tv, or iTunes University for some of my offerings. I want to be Earth's virology professor.

TWiV 478: A pox on your horse

1 Comment / This Week in Virology / By

The TWiV team explains how infectious horsepox virus – likely the ancestor of smallpox vaccines – was recovered from chemically synthesized DNA fragments. <span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”></span>&lt;span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”&gt;&lt;/span&gt;&amp;lt;span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”&amp;gt;&amp;lt;/span&amp;gt;&amp;amp;lt;span data-mce-type=”bookmark” …

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HPV vaccines do not encourage risky sexual behavior

5 Comments / Basic virology, Information / By

  The human papillomavirus (HPV) vaccines save lives by preventing lethal cervical and anogenital cancers. If Henrietta Lacks had received an HPV vaccine, she would not have succumbed to cervical cancer. Yet not enough young men and women receive the vaccine. An obstacle to more widespread adoption of the HPV vaccine is that some parents …

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TWiV 477: Raiders of the lost Arc

This Week in Virology / By

The TWiVodrome explains how a gag-like protein from a retrotransposon forms virus-like particles that carry mRNA within vesicles across the synapse. <span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”></span>&lt;span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”&gt;&lt;/span&gt;&amp;lt;span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”&amp;gt;&amp;lt;/span&amp;gt; Click arrow to …

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Metabolic manipulations in virus-infected cells

2 Comments / Basic virology, Information / By

The large quantities of viral macromolecules and virus particles that are produced in an infected cell impose heavy demands on the host. Synthesis of the building blocks of a virus particle – nucleotides, amino acids, and sometimes fatty acids – requires energy, typically in the form of ATP. Synthesis of viral proteins and genomes, and …

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