Author name: Vincent Racaniello

I'm Professor of Microbiology and Immunology at Columbia University in New York. I run a research lab where we study poliovirus, rhinovirus, and other RNA viruses. I also love teaching about viruses - check out virology.ws, microbe.tv, or iTunes University for some of my offerings. I want to be Earth's virology professor.

TWiV Special: David Tuller is PACEman

3 Comments / This Week in Virology / By

David Tuller returns to provide an update of his investigative work to expose the methodological and ethical problems with the PACE trial for ME/CFS. <span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”></span>&lt;span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”&gt;&lt;/span&gt;&amp;lt;span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”&amp;gt;&amp;lt;/span&amp;gt;&amp;amp;lt;span data-mce-type=”bookmark” …

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TWiV 507: The fusion of form and function

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The TWiV team discuss the biology of Ebola viruses, and how localization of the membrane proteins of vaccinia virus drive function: the fusion machinery sits at the tips of virions, and binding proteins are at the sides. <span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”></span>&lt;span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: …

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Viral glycoproteins are not always randomly distributed

2 Comments / Basic virology, Information / By

The membranes of enveloped viruses contain embedded proteins that are essential for attaching to cell receptors and fusing with cell membranes. We generally view these glycoproteins as evenly distributed over the surface of the virus particle, as illustrated for influenza virus. But many more envelope glycoproteins are involved in attachment and entry of larger viruses, …

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TWiV 506: A Cafeteria full of jelly rolls

1 Comment / This Week in Virology / By

The TWiVniks explain how the three-dimensional structure of the giant Cafeteria roenbergensis virus suggests a new mode of assembly, and the apparent elimination of dengue fever in an Australian city by release of mosquitoes harboring Wolbachia. <span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”></span>&lt;span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” …

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TWiV 505: Rosebola

This Week in Virology / By

The TWiV hosts review persistence of Ebola virus after the end of the Liberian outbreak, and the potential role of two herpesviruses in the pathogenesis of Alzheimer’s disease. <span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”></span>&lt;span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”&gt;&lt;/span&gt;&amp;lt;span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: …

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