October 2011

Results of the Blood XMRV Scientific Research Working Group

The Blood XMRV Scientific Research Working Group was formed to design and carry out a study to determine whether xenotropic murine leukemia virus-related virus (XMRV) posed a threat to blood safety. Phase III results were published on Sept. 22, 2011 in Science. In an upcoming webinar study leaders Graham Simmons and Mike Busch will present …

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The Lazarus virus

There is an excellent question in the comments to “Are all virus particles infectious?“: if the particle-to-PFU ratio for a virus stock is 10,000:1, and I infect 1,000,000 cells with 10,000 particles, how many plaques would I expect to observe? Answering this question provides insight into the particle-to-PFU ratio of viruses. If we take 10,000 particles …

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TWiV 152: Viromes in the effluence of society

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit Vincent, Alan, and Rich cover the virome of raw sewage, and a baculovirus gene that causes caterpillars to climb to their doom. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV152.mp3″] Click the arrow above to play, or right-click to download TWiV 152 (50 MB .mp3, 83 minutes). Subscribe to TWiV (free) in iTunes , …

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David and Goliath: How one cytokine may take down influenza

This article was written for extra credit by a student in my virology course. by Alexandra Jacunski Recent research has suggested a new method of flu prevention and treatment: the administration of granulocyte macrophage-colony stimulating factor (GM-CSF) to the lungs of mice significantly reduced flu symptoms and prevented mortality after a lethal dose of influenza virus. …

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TWiM 17: Debugging endosymbiosis

Hosts: Vincent Racaniello, Michael Schmidt, and Elio Schaechter. Vincent, Michael and Elio focus on endosymbiosis: the rapid spread of Ricekttsia in whitefiles, and a metabolic patchwork in nested symbionts of mealybugs. [powerpress url=”http://traffic.libsyn.com/twimshow/TWiM017.mp3″] Click the arrow above to play, or right-click to download TWiM #17 (51 MB, .mp3, 70 minutes). Subscribe to TWiM (free) on iTunes, Zune Marketplace, via RSS feed, …

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